Gaining Insight Into Reactivity Differences Between Malonic Acid Half Thioesters (MAHT) and Malonic Acid Half Oxyesters (MAHO)
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منابع مشابه
Decarboxylative ketone aldol reactions: development and mechanistic evaluation under metal-free conditions.
Malonic acid half thioesters (MAHTs) and malonic acid half oxyesters (MAHOs) are shown to undergo decarboxylative nucleophilic addition reactions with ketone and aldehyde electrophiles in the presence of stoichiometric or catalytic quantities of triethylamine at room temperature. The ability to perform these reactions under metal-free conditions has enabled a detailed mechanistic analysis of th...
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ژورنال
عنوان ژورنال: Chemistry - A European Journal
سال: 2017
ISSN: 0947-6539
DOI: 10.1002/chem.201605148